Further, the number of one-to-one orthologues with mouse and chimp did not differ between the set of HLOF genes and all human protein-coding genes on Ensemble (Chi-square test with Yates's correction: N.S. for both comparisons).
Pseudogene transcription has also been reported in other species including fly, mouse, cow, and chimp [4].
We observed the same trend by choosing 4 relatively well-studied mammals: human, mouse, rat, and chimp, and used the "all" information (without removing those peptides labeled as "novel", and including all paralogous information) provided by Ensembl to perform the same analysis.
Investigation of mammalian genomes showed regions of chromosome 8 of the mouse (and of chimp chromosome 16, cow chromosome 18 and dog chromosome 5, data not shown) to be comparable in gene order and intergenic distance to the genes on human chromosome 16.
Our previous work reported that similar intergenic distances were present at orthologous positions of bidirectional promoters in pairwise comparisons between human and mouse or human and chimp.
Comparison of the identities of POP2-related proteins from all species examined reveals that the number of POP2 PYD-related sequences increases in number during mammalian evolution (one in mouse and four in chimp and human).
Using the alignment, we generated a phylogenetic maximum-likelihood tree of mouse, rat, chimp and human orthologs.
They'd like to see Silver and her colleagues replace the mouse HARE5 with the human and chimp HARE5 a feat the Duke group has yet to succeed in doing.
These observations are consistent with our notion of relatively higher evolutionary divergence between human and mouse as compared to human and chimp.
For PicTar, the result based on conservation in human, chimp, mouse, and rat was chosen.
