Sentence examples for both morphogenesis and tumorigenesis from inspiring English sources
Together, these functional analyses in different representative organisms along the phylogenetic tree indicate that the ancestral function of Brachyury was the promotion of cell movement and adhesion, which are fundamental for both morphogenesis and tumorigenesis.
Our results thus indicate that in addition to its anti-apoptotic function, Bcl-2 may be also involved in EMT during normal morphogenesis and tumorigenesis.
We conclude by emphasising the urgent need to identify the molecular targets of the progesterone receptor, and to determine whether these targets are modulated differently by the progesterone receptor isoforms (A and B) during mammary morphogenesis and tumorigenesis.
In recent years, increasing studies indicate that miRNAs have crucial functions in specific cellular processes such as differentiation, morphogenesis, and tumorigenesis and they are also considered as oncogenes and tumor suppressors [ 9– 12].
Our findings, together with the striking similarities in mammary development and tumor phenotypes between Becn1 +/− and MMTV- Tnfrsf11a (or MMTV- Tnfsf11) mice, suggest that the TNFRSF11A pathway may mediate the impact of monoallelic Becn1 loss on mammary cell hierarchy, morphogenesis and tumorigenesis.
This gene is a regulator of mammary epithelial cells apoptosis during both morphogenesis and involution of the mammary gland.
It also regulates both morphogenesis and gene expression in developing extraocular muscles [ 35].
GCN pathway is involved in both morphogenesis and biofilm formation in response to amino acid deficiency.
Nevertheless, the molecular mechanisms mediating p63 function both during development and tumorigenesis remain to be fully characterized.
TGF β mediated induction of EMT processes is associated with specific stages of morphogenesis and during tumorigenesis by activating downstream signaling pathways in both Smad-dependent and Smad-independent mechanisms.
In addition, several presentations addressed signaling molecules involved in branching morphogenesis and mammary tumorigenesis.
