One hundred and sixteen rhesus monkeys (Macaca mulatta) underwent behavioral testing (Screening, Time 1), and 36 (26 females) monkeys were selected to undergo a brain imaging experiment (FDG-PET, Time 2).
Based on their similarity to human HLA-DRβ1* alleles determined by genotyping [12], eighteen monkeys were selected for this study and classified into different immunization groups (Figure 1).
Monkeys were selected to be naive to prior mycobacterial exposure on the basis of a negative Mantoux skin reaction using Old Tuberculin Statens Serum Institutee (SSI), Copenhagen), a negative result in the Primagam® kit measuring M.bovis/M.avium PPD specific IFNγ release in whole blood cells (Biocor Animal Health, Omaha, Nebraska, USA), and clean chest X-rays lacking any signs of TB (see below).
Two monkeys were selected to receive daily oral treatment with levodopa and benserazide (25 mg/kg of Madopar, Roche, France).
Based on blood glucose (<90 mg/dL) and other biochemistry tests, five healthy young cynomolgus <span class="lh">monkeys were selected for the normoglycemic group (Table 1).
The other five cynomolgus monkeys were selected from spontaneously naturally developed and already insulin-treated diabetic animals with blood glucose >150 mg/dL.
Boundaries of corresponding subdivisions defined in the 3 monkeys were selected and the variability range for each subdivision estimated by the surface between the most dorsal and the most ventral limits of the area selected.
Both players were selected fourth overall.
It quoted the director of the Iran Space Agency, Hamid Fazeli, as saying this month that "because of biological similarities between humans and monkeys, the latter were selected for the space mission".
Healthy adult male rhesus monkeys (Macaca mulatta) were selected and randomly stratified on basis of age and body weight over 4 groups of 6 animals each.
