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In this sense, both models demonstrate that internal feedbacks play a critical role in controlling river responses to environmental change over historic and Holocene timescales.
Although different tissues are affected by Mdm2 reduction or deletion, both models demonstrate that Mdm2 inhibition of p53 is required for embryogenesis, after birth, and in adulthood.
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Regardless, genetic deletion of Puma, a pro-apoptotic Bcl-2 family protein under p53 control, is strongly protective in both models, demonstrating that the models are capable of detecting functional contributions of p53-regulated pro-apoptotic genes to neuronal death.
Time domain simulation results on both load models demonstrate that the proposed VSI accurately indicates voltage instability and outperforms a conventional VSI which is based on a constant power load model.
Although the area of Irish ice cover varied between 27 and 15 kya, with a possible retreat 24 23 kya followed by re-advance [ 7], the similar population dynamics shown by both of our models demonstrate that Irish brown bears would probably have disappeared even if they had only been restricted to the southwestern refugium for part of the LGM.
Both cellular and animal models demonstrate that αSyn can affect ETC components and thereby lead to the excessive production of ROS in dopaminergic neurons (8).
Using data from mammals, phylogenetically corrected general linear models demonstrate that both multiple paternity and alpha paternity, but not extra group paternity, relate to testes size.
Our set of simple models demonstrate that both aggregated and expert rules can enable accurate collective solutions to challenging problems [9], as this has also been found in human group decision-making [27], [28].
- Specifically, experimental and clinical data in humans and animal models demonstrate that both prenatal stress and prenatal overexposure to GCs are associated with reduced birth weight, possibly via related actions in a shared pathway such as feeding behavior.
Our studies in both RCC and prostate tumor models demonstrate that the combination of genistein with primary tumor irradiation is a more effective and safer therapeutic approach as the tumor growth and progression are inhibited both in the primary and metastatic sites.
Our studies in both RCC and prostate tumor models demonstrate that the combination of genistein with primary tumor irradiation is a more effective and safer therapeutic approach as the tumor growth and progression are inhibited both in the primary site and metastatic sites.
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