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Direct sequencing and heteroduplex analysis are both methods with sensitivity well over 90% for coding region and splice site mutations; however, the problem of genomic rearrangements in BRCA1 remains.
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Cultivated primary endothelial cells added to blood samples were detected with both methods with a similar sensitivity and a strong linearity with increasing numbers of endothelial cells.
It also demonstrates a hybrid feature selection method combining GA-based feature selection methods with sensitivity analysis.
This well known attenuation effect may be substantial for measurement methods with sensitivities in the range 0.60 0.70 and specificities in the range 0.90 0.95, as often is the case for methods employed to assess environmental exposures [ 9].
For example, if 20% of workers are exposed to an occupational hazard that produces a real increase in the risk of lung cancer of 50%, a nondifferential misclassification arising from an exposure estimation method with sensitivity and specificity both equal to 80% will reduce the observable increase in lung cancer risk to about 20%.
While the threshold method is 100% sensitive, Mov-Avg Cusum is the worst performing method with sensitivity of 77% to 97%.
The results are compared to those of the conventional method with sensitivity analysis using the finite difference method.
The measurement performance is linked to the closed-loop sensitivity functions and a controller design based on a pole placement method with sensitivity functions shaping is proposed.
We settled some options of the inversion method with sensitivity studies: tree covers are simulated with 4-tree scenes, expression h has six coefficients ci and the interpolation is the continuous first derivative interpolation method.
Particularly for serum iron, an iron ferrozine complex method was used with sensitivity of 5 μg/dl; serum transferring was measured using a turbidimetric method with sensitivity of 70 mg/dl.
For example, the interactions between members of the flagellar machinery are detected by this method with sensitivity and specificity higher than those obtained using the pairwise similarities alone (Juan et al, 2008).
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