Sentence examples for both methods and found from inspiring English sources
We analyzed DNA extracted from 77 FFPE melanoma samples with both methods, and found a high positive correlation (R = 0.94) of BRAF-M% (Additional file 2A).
To prove that BisPCR is comparable to traditional targeted bisulfite NGS approaches, we measured DNA methylation at the H19 locus in mouse genomic DNA using both methods and found nearly identical results (Additional file 2: Figure S2).
27, 31 In the current study, we used both methods and found a strong correlation between them (r = 0.764; Figure 4), suggesting that these methods can be used alternatively.
In our study we evaluated both methods and found visual assessment afforded higher accuracy (76%) than any SUV threshold with a good compromise between sensitivity (64%) and specificity (89%); while increasing the threshold from 1.5 to 2.5 decreased sensitivity (67%to51%1%) and increased specificity (80%to91%1%).
While the actual cost of typing a single marker by either method may vary greatly depending on choice of particular reagents and plastic ware, we applied similar criteria to reagent selection for both methods and found similar costs for PCR amplification (not shown, but details can be provided by the corresponding author upon request).
We have since tested both induction methods and found them to produce similar results, and we have added a comment in the Materials and methods section to reflect this: "Induction of protein expression both with and without the raffinose step gave similar mutation rates".
To investigate cell migration, we analyzed the number of human cells at different regions along the spinal cord (see Methods) and found that both hCNS-SCns and hFb migrated at least 3 mm, in each direction from the edge of the lesion, but significantly more hCNS-SCns were found at greater distances from the epicenter in comparison to hFb (Fig. 3A and B).
We therefore determined the PGA for each patient iCluster in both discovery and validation cohorts (see Methods), and found that genomic instability differs significantly between each genomic subtype in both datasets (Suppl. Fig. 12): Kruskal Wallis p = 4.463 e − 11 (Cambridge); p = 0.0009246 (Stockholm).
In our study we investigated kaolin activated citrated samples together with non-activated citrated samples in relation to the elapsed times of 0, 15 and 30 minutes to compare both methods and to find out if there is an impact of time on results of thrombelastography.
In addition, we compare both two-stage methods and find that our two-stage method will lose power because we only use part of samples in both two stages.
