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Graphs show quantification of both markers over time for Golgi 1 to 4. Results are representative of two independent experiments.
Graphs show quantification of both markers over time for Golgi 1. Results are representative of two independent experiments.
Graphs show quantification of both markers over time for Golgi 1 and 2. Results are representative of three independent experiments.
A two-order polynomial model for LC3 and cleaved Caspase-3 staining revealed direct increase in both markers over time, with no significant difference between any of the treatment groups and only a marginal difference with regard to cleaved Caspase-3 expression in the co-treatment group (P=0.11).
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We found a strikingly stable antibody status for both the total number of positive markers over time (Figure 1C) as well as for each single antibody (Figure 1D) per individual patient.
Baseline well arsenic, a long-term measure of arsenic exposure, was positively associated with baseline levels of both sICAM-1 and sVCAM-1 and with changes in the two markers over time.
Until recently, experimental evolution has been limited to measuring phenotypic changes, or to tracking a few genetic markers over time.
By measuring improvements in these surrogate markers over time, governments can track progress towards their overall goal of reducing maternal mortality.
Validation of the markers over time scales of milliseconds was achieved by showing that common types of sleep-EEG phasic events could be detected by recurrence analysis.
We did not observe any significant changes in discriminatory capacity of the markers over time.
One prerequisite for routine use is the stability of markers over time.
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