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In fact, both markers displayed a trend towards lower expression in hyperglycemic conditions.
The significant prognostic role of CRP and NLR is supported by the evidence that the levels of both markers displayed a linear relationship with the progressing stage of tumor and Child-Pugh classification, known as the two key prognostic factors for HCC.
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Importantly, both of these routinely used markers displayed a lower prognostic accuracy than S100A6, highlighting that new and innovative biomarkers might be superior in this setting than currently used markers.
The iPBS markers displayed a higher proportion of polymorphic loci (PPL = 92.5%) than the ISSR markers (PPL = 84.9%).
These markers displayed a high level of polymorphism overall (6.67 alleles/locus), though this was slightly lower within populations (3.10 4.88 alleles/locus).
The other significant markers displayed a low MAF (4 to 7%).
These markers displayed a homogeneous distribution at the cell surface in cells pre-treated with anti-CD3 antibodies.
In contrast, kidney endothelial cells defined by the latter markers displayed a lower expression of CD146.
Underlined markers displayed a transcriptional regulation pattern consistent with the prediction from the literature.
All SSR, 11% of RBIP and only 2.6% of SNP markers displayed a Minor Allele Frequency (MAF) below 1%.
The markers displayed a remarkably similar pattern in the G93A SOD1 mouse model of ALS with increases detected at preclinical stages.
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