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Increasing intra-abdominal pressure increased both lung elastance and chest wall elastance.
We suggest that a rational approach to the treatment of ALI/ARDS requires the knowledge of both lung elastance and chest wall elastance.
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Emphysema is a slowly progressive degenerative lung disease involving fragmentation and depletion of elastic fibers, loss of lung elastance, and architectural destruction with ectasia, tortuosity, and loss of bronchioles irrespective of localization or morphological type.
APRV also preserved lung elastance and reduced lung injury by histopathologic scoring.
APRV maintained a normal lung elastance and an open, homogeneously ventilated lung without increasing lung stress.
End-expiratory pressure was used for calculations of lung elastance and transpulmonary pressures.
Thus, we do not need to know pleural or esophageal pressure to estimate lung elastance and changes in transpulmonary pressure.
Prone position is used to recruit collapsed dependent lung regions during severe acute respiratory distress syndrome, improving lung elastance and lung gas content.
In contrast with our hypothesis, we found a change in lung elastance and functional residual capacity even in the absence of lung recruitment.
As a consequence, we do not need to measure pleural or esophageal pressures to estimate lung elastance and changes in transpulmonary pressure.
In contrast with our hypothesis, we found that even when recruitment is negligible, prone position ameliorates lung elastance and increases functional residual capacity, mainly through a different, more homogenous distribution of lung aeration.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com