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Additionally, we review experiments on effects of P, N and N + P addition on both low affinity and high affinity methane oxidation.
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AtNRT1-1 is largely constitutively expressed and encodes a dual-affinity NO3- transporter, performing both low-affinity and high-affinity transport, mediated by phosphorylation [ 36].
The observation that the pause affects almost all dopamine neurons makes it a powerful negative signal that would phasically stop stimulation of both low affinity D1 and high affinity D2 receptors.
The obtained series of compounds exhibits low affinity and activity both at opioid receptors and as cyclooxygenase (COX) inhibitors.
IDPs are thus able to perform low affinity and high specificity binding18.
For instance, bidirectional sugar transporter SWEET3a, which was identified to be a DEG located on the region of qPGWC5 (qDEC5), is involved in carbohydrate transmembrane transport process (http://www.ebi.ac.uk/QuickGO/) and predicted to mediate both low-affinity uptake and efflux of sugar across the plasma membrane (http://string-db.org/newstring_cgi/).
In the 'closed' conformation, representing the 21% E-FRET population, both the low affinity 'DLG' and the high affinity 'ETGE' motifs of Nrf2 are bound to the Keap1 dimer.
On the other hand, both the low affinity of Ni and Co for these oxide minerals and the region's geomorphology allowed for their migration towards the drainage network to the regions of sediment accumulation at lower altitudes during the landscape's evolution.
Previous work has indicated that ordering of helix α3 (residues 65−78) is important for NikR binding to DNA (4, 10), and both low-affinity site types 2 and 3 utilize residues from helix α3 or the following loop.
Fungal AMTPs are in a phylogenetic clade by themselves that includes both low-affinity [ 27- 30] and high-affinity [ 31- 35] AMTPs (MEP γ clade [ 10]).
The results showed that the previously hypothesized "portal region" could be readily used for the dissociation of ligands at both the low affinity site and the high affinity site.
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