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For both lines, we observed identical sequences.
In both lines, we observed examples of intestinal epithelial hyperplasia and definitive neoplasia (Fig. 5G).
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In both cell lines, we observed that PF477736 abrogated TPT-induced cell cycle arrest.
In both transgenic lines we observed a reduction in transcript accumulation of the genes evaluated, with the exception of AOX1A.
Here, in both examined cell lines we observed that the allosteric activator of the CaSR NPS R-467 increased cell growth and this effect was inhibited by adding the CaSR antagonist NPS 2390.
In both cancer cell lines, we observed induction apoptosis and sensibilization by PTX.
In both BH3 Tg lines, we observed a decreased proportion of DP thymocytes and an increased proportion of SP thymocytes compared to wild-type littermate controls.
Interestingly in both the cell lines we observed S-phase arrest at the lower doses of MFX and CFX (100, 200 μg/ml) at 24 h and 48 h respectively.> -wrap-foot>> -wrap-foot> Values represent the percent of population in each phase.
In a panel of cell lines we observed ubiquitous FRS2 and FRS3 transcript and protein expression in both benign and malignant cells.
In some lines, we observed increased or broader intestinal expression of cyp-35B1 GFP cyp-35B1 GFPintreated animals.
Despite the successful hematopoietic differentiation from all nine different hiPSC lines, we observed a high variability in differentiation efficiency.
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