Sentence examples for both linear and conformational from inspiring English sources
BEEPro [ 8] adopted a linear averaging scheme on 16 properties to recognize both linear and conformational epitopes.
The Ro52 autoantigen is extraordinarily immunogenic, and its autoantibodies are directed against both linear and conformational epitopes.
Both linear and conformational epitopes for neutralizing antibodies have been mapped to aa residues 578 607, 452 617, and 458 607 in the C-terminal portion of ORF2.
After chemical/heat treatment of the protein samples, WB will only detect the linear epitopes on the N protein, while ELISA detects both linear and conformational epitopes.
Since polyclonal antibodies are likely to bind both linear and conformational epitopes along the entire length of the SEB protein, these results suggested that soy-mSEB epitopes are intact.
A later method called ElliPro (Ponomarenko et al., 2008) takes advantage of the PI (Thornton et al., 1986) and makes use of a residue clustering algorithm to predict both linear and conformational B-cell epitopes for a protein sequence or protein structure.
Previous studies have shown that region A-HVR of the viral E2 glycoprotein binds SR-BI 20– 22; we therefore used a panel of mAbs targeting linear and conformational E2 epitopes to study the effect of IFNα on glycoprotein conformation.
Linear and conformational B-cell epitopes were identified.
Finally, we also predict the linear and conformational B-cell epitope.
Our protein contains several linear and conformational B cell epitopes, which suggests the antibody triggering property of this novel vaccine.
However, N184S and D445N mutations were also involved in linear and conformational B-cell epitopes, respectively that should be considered in vaccine design.
