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Both levels of expression correlated highly when data from all animals was pooled (r = 0.963; P < 0.01).
Thus by looking at both levels of expression we were able to identify the most thorough list of miRNA-target pairs.
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This would provide information on both levels of transgene expression (by fluorescence) and potential local changes in mammary tissue 'content' (by luminescence) in these new models.
We show that PP1γ is indeed subject to a striking alteration in both its levels of expression and localisation, both as lesions develop, and in the tumour derived cell lines.
The different lines present variability in both, the levels of expression of activated AKT and the degree of chimaerism, number of cells per duct expressing the transgene.
However, a probable mechanism for this distorted signaling appears to involve Itk, which had both higher levels of expression and phosphorylation at tyrosine 511 in Jurkat E6.1 T cells than in HuT78 T cells and APBTs (Figure 9).
Since Pgp is constitutively expressed on lymphocytes from RA patients, and its expression is correlated with disease activity, both basal levels of expression and upregulated levels upon long-term administration could be limiting factors in sustaining long-term efficacy [ 56].
The results showed that in the ad libitum-fed state, both phenotypes had comparable levels of expression of rPFH Ucn3, but the obese rats had lower levels of expression of VMH CRF2-R.
Further characterization demonstrated that translational coupling functions at both low and high levels of expression and that the response signal is proportional to the amount of target gene product.
Both genes had minimal levels of expression in nighttime samples.
In the whiskers area of both strains the highest levels of expression were detected for Irf7 at 1 dpi.
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