Exact(2)
The evidence obtained in the three APP transgenic mouse models is compelling and holds potential to be translated to both late onset AD and dominantly inherited AD.
Point mutations in the LRRK2 gene are frequently associated to PD, and they are found in both late onset familial and sporadic PD.
Similar(58)
In both late-onset Pompe patients and KO mice, skeletal muscle fibers contain large areas of undegraded autophagic material [11] [13].
PSMD9 mutations rarely cause T2D and common variants are linked to both late-onset T2D and maturity-onset-diabetes of the young (MODY3).
In the clinical setting, the presence of titanium particulate, secondary to corrosion of spinal implants could serve as the impetus for both late-onset inflammatory-infectious complications and long-term osteolysis in the established posterolateral fusion mass [ 17].
These results indicate that although a younger age at onset of cannabis use correlated with disruptions in thalamo-cortical connectivity in CHR, in the group analyses, CHR early-onset cannabis users showed similar patterns of connectivity to both late-onset and cannabis naïve CHR.
Goldwurm S, Di Fonzo A, Simons EJ et al: The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor.
The 12q13 SNPs are significantly associated with T1D in both early and late onset T1D data sets with similar OR estimates (Table S1).
The data from this study confirm that, in both early and late onset PE, maternal serum levels of sFlt-1 and sEng are higher, and PlGF lower, in women presenting with PE [1] [3].
Perinatal factors like PROM and meconium stained liquor were strongly associated with positive blood culture in both early and late onset sepsis (p ≤ 0.001).
Gestational age and small gestational age by birthweight were not found to influence rate of positive blood culture in both early and late onset neonatal sepsis (Table 1).
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