Sentence examples for both its expression and from inspiring English sources

At present, little is known regarding the physiological regulation of ADAR2 expression, however it has been shown that both its expression and activity are markedly enhanced in response to glucose in pancreatic islets and beta-cells [ 33].

IFI16 also binds to the androgen receptor to up-regulate both its expression and activity (18).

In vertebrates, mir-9a has a quite different role in positively regulating neurogenesis, indicating that both its expression and function has changed significantly in the vertebrate group or this developmental role of mir-9a is particular to the insect group.

In a recent report, AMPK expression was first described in the human thyroid gland and both its expression and activity were shown to be strongly up-regulated in PTC [ 21].

In addition, the oxons also bind directly to the m2AChR, affecting both its expression and its ability to elicit cellular signals (Howard and Pope 2002; Huff et al. 1994).

Instead, the results presented are consistent with a role for MULAN at the level of trafficking regulation –both its ectopic expression and knockdown led to altered mitochondrial distribution, without having apparent effects on the microtubule network.

These experiments confirmed both its expression in normal articular cartilage and a highly significant decrease in Tob1 transcript levels in osteoarthritic samples (7.8-fold; P < 0.001; Fig. 3b).

Considering that gene amplification is a tumor-specific event during malignant transformation, and that SOX2 locus is subjected to this alteration in other tumors, namely of the lung and esophagus [ 17], we hypothesized that SOX2 amplification could explain its expression and heterogeneity, both within and among gastric tumors.

Such a view of Christ appeared occasionally in the writings of Augustine, but it was in men like Bernard of Clairvaux that it attained both its fullest expression and its most-adequate harmonization with the dogmatic view.

It has been shown previously that the calcium-activated phosphatase calcineurin is both necessary and sufficient to induce cardiac hypertrophy and that both its protein expression and phosphatase activity are increased in response to hypertrophic stimuli [ 28, 35].

13 Like the differences between WAT types, MAT is also distinct in both its gene expression and ability to respond to nutritional status.