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The success of an NPI or a set of NPIs depends on both its efficacy and the feasibility of implementing it with relevant populations.
M-VIVIE was tested on different kinds of real video clips to assess both its efficacy and efficiency.
Furthermore, NISC-6 effectively induced apoptosis in human melanoma cells, inhibited tumor growth by ∼69% in a melanoma mouse xenograft model, and showed excellent compliance with the Lipinski' rule of five, suggesting both its efficacy and drug-like behavior under physiological conditions.
These results suggest that NS-018 will have therapeutic benefit for MPN patients through both its efficacy and its reduced hematologic adverse effects.
Thus, in various settings tamoxifen is an inhibitory ER ligand in the breast, and this property explains both its efficacy and its widespread use.
A phase I study, similar to that of romiplostim, showed a dose-dependent rise in platelet counts [ 57] and a randomised double-blind placebo-controlled phase II study confirmed both its efficacy and safety [ 53].
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The treatment with OnabotA (Botox®, provided by Allergan) is an important therapeutic option both for its efficacy and for the safety profile [14].
When a breakthrough medical technology is discovered, the question arises as to whether to accept the possible risks involved, or to defer implementing the innovation until more data is available, and, specifically, until others have taken up the innovation and demonstrated both its efficacy, its relative safety and market acceptance.
Some clinical studies have given evidence to this hypothesis (Agnoli et al 1989; Spiers et al 1996) and there is a proposal for studying citicoline in mild cognitive impairment (MCI) with the aim of confirming both its efficacy in these patients and a possible role as a retardant agent for the cognitive deterioration of the eventual subsequent dementia (Abad-Santos 2002).
We also showed that in vitro optimization of a bacteriophage towards a clinical strain improved both its efficacy on in vivo treatments and its host range on a panel of 20 P. aeruginosa cystic fibrosis strains.
Both brands secondarily claim to beat their rival at its own game, with Palmolive promoting its efficacy and Dawn its mildness.
More suggestions(15)
both its appropriateness and
both its efficiency and
both its performance and
both its limitation and
both its power and
both its restraint and
both its intelligence and
both its scope and
both its style and
both its league and
both its pathology and
both its founder and
both its scapegoat and
both its strength and
both its revenue and
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com