Sentence examples for both isoforms were overexpressed from inspiring English sources

To our surprise, we observed that MEF lacking Bax and Bak also showed reduced colony formation when both isoforms were overexpressed from a single plasmid and at the moment, we can only speculate that these cells may either activate Bok under these conditions or die by necroptosis (19 ).

RT-PCR analysis demonstrated that while both ey(2a) and ey isoforms were overexpressed to similar extent (Fig. 4C, panel ey), induction of ey-target genes mediated by Ey(2a) was lower compared with Ey (Fig. 4C, compare lanes 2 and 3 of each panel).

Figure 1A shows that PLD2 had a higher basal activity (1.6-fold) than PLD1 in the presence of glucose (25 mM) when PLD isoforms were overexpressed in HEK-293 cells.

The antibody binding to nuclear β- and γ-actins is low even when this isoforms were overexpressed (Online Resource 3 insert in 'ESM'ESM

Ex5-MBNL1 42–4 3 isoforms were overexpressed in DM1 muscle 1.9- to 17.3-fold compared with controls, whereas ΔEx5-MBNL1 37L–40–41 transcripts vary over the range from 0.38 to 1.40.

To further verify their respective role, the four distinct C10 isoforms were overexpressed in the TRAIL-sensitive SH-EP and SK-N-AS S-type NB cells.

To generate an experimental setup with a very-low rate of caspase-8 activation, short c-FLIP isoforms were overexpressed in HeLa-CD95 cells.

Trisk 95 and Trisk 51, the two major skeletal muscle triadin isoforms, were overexpressed in vivo using injection of adenovirus into newborn mice.

We have generated a SALL4 transgenic mouse model in which SALL4B, one of the SALL4 isoforms, is overexpressed.

The finding of ∆Np73 isoforms being overexpressed in several tumours supported this vision [ 13, 21].

In particular, several lines indicate that Akt isoforms are overexpressed or hyperactivated in a broad range of human cancers through dysregulated activation of PI3K/Akt pathway.