Cold distributes to both intravascular and extravascular volumes, whereas ICG remains intravascular.
Cold is distributed throughout both intravascular and extravascular volume, whereas ICG remains in the intravascular volume.
Therefore, the I-albumin value at 5 min provides a quantitative measure of intravascular volume whereas the I-albumin value provides a measure of the sum of both intravascular and extravascular albumin.
These effects may explain why FgnE selectively disrupts tumour endothelium, causing widespread intravascular thrombosis and tumour necrosis in vivo (Brown et al, 2002).
These protease inhibitors have major roles in physiologic and pathologic processes such as angiogenesis, intravascular fibrinolysis, wound healing, and tumour invasion and metastasis (Janciauskiene, 2001; Brantly, 2002).
Scientists also discovered higher levels of 27HC in both healthy breast tissue and tumour cells in women with breast cancer.
The final clinically important outcome is destruction of red cells, which is both intravascular (witness haemoglobinuria) and extravascular [witness hyperbilirubinaemia (Fischer et al, 1985)].
Both tumour and non-tumour pathology cases are discussed.
In the present study we therefore characterized the differential mRNA expression of HEPACAM1 and 2 in laser microdissected frozen tissue samples and HEPACAM1 protein expression in normal mammary gland epithelium, adenomas and metastatic canine mammary carcinomas, intravascular tumour cells and lymph node metastases.
In conclusion, we believe that the fact that IBC has fast growth in the breast gland, combined with a specific growth pattern (intravascular tumour expansion and enhanced cell migration) and numerous metastases at diagnosis, corroborates the self-metastatic expansion model.
