Intact and total IGFBP-3 levels were correlated with age and smoking.
Means ± standard deviations of intact and total IGFBP-3 levels (ng/mL) were 1,044 ± 234 and 4,806 ± 910, respectively.
Plasma intact and total IGFBP-3 and IGF-I levels were measured by enzyme-linked immunosorbent assay methods.
Here, we examine the association of breast cancer risk factors with intact and total IGFBP-3 levels.
and DPP4 inhibitor (DPP4i; valine pyrrolidide, 0.01 mM final concentration, a gift from Novo Nordisk, Bagsværd, Denmark) for analyses of glucagon, intact and total GLP1 and intact glucose-dependent insulinotropic polypeptide (GIP).
At each time-point, blood is drawn for serum/plasma analyses for glucose, insulin, c-peptide, glucagon, intact and total GLP-1 and GIP, respectively.
Contrary to our expectations, the associations of intact and total IGFBP-3 levels with breast density do not seem to mirror the IGFBP-3-breast cancer associations in the study of Rinaldi and colleagues [ 15].
This is the first epidemiologic study to examine the association of intact and total IGFBP-3 measurements with a large set of breast cancer risk factors, including mammographic breast density.
Therefore, the PCR, using degenerate primers directed at the OR gene family, and subsequent sequencing were used to estimate both the percentage of intact and the total number of OR genes in the avian genomes.
Table 3 shows correlations of mammographic breast density with intact, fragmented, and total IGFBP-3 levels.
