The biocompatible, biodegradable, and highly tunable synthetic polymer, poly d,l-lactide-co-glycolide) (PLGA), is widely used as a vector for sustained drug delivery, however, issues such as insufficient loading and inappropriate burst release kinetics have dogged progress into the clinic for small hydrophilic drugs such as 5-FU.
The results show that the alloy steel bar used for the half-shaft did not follow specifications, with a consequent lower strength and resulting in a material with insufficient loading capacity and fatigue resistance.
However, during the melt season, there was no diurnal change in water pressure; however, the high water pressure conditions may have been ideal for icequakes during the morning (Stage 4) and evening (Stage 2), whilst the during the early morning (Stage 3) and the slip phase (Stage 1) there was insufficient loading for icequakes to occur.
An insufficient loading of the Fe S cluster onto the protein was hypothesized to result in a very low enzyme activity, since the Fe S cluster machinery in S. cerevisiae failed to recognize it as an apoprotein (Benisch and Boles 2014).
Insufficient loading of unregulated dopamine into vesicles, therefore, could result in the observed altered dopamine metabolism.
However, insufficient load-bearing capability and a high rate of intraoral wound dehiscence were found in the majority of the study animals.
We found the interfacial carbon film between the CR3 coating and steel substrate, which caused poor bonding and consequently insufficient load-bearing capability of the coating.
than individual CNTs due to the weak interfacial shear strength between adjacent shells, nanotubes, and nanotube bundles, causing insufficient load transfer.
Directly spun CNT fibers, however, generally include amorphous carbon and weak shear interaction between tubes or bundles, thereby causing insufficient load transfer.
FWD test results for all three projects yielded much higher deflections than the target design deflections, indicating insufficient load bearing capacity.
