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Application of 40 µ m MPEP (n = 9) for 20 min prior to HFT resulted in a significant impairment of both induction and expression of LTP (Fig. 2A; anova: within factor F1,19 = 10.367, P = 0.0001; between factor F1,19 = 1.806, P = 0.0373).
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Both the induction and expression of Th2 immunity can be modulated by environmental agents that affect the cytokine milieu in the airway mucosa and/or the draining lymph nodes.
In WT mice, >50% of IL-10+ T cells were also producing IL-4 (Fig. 2C), reflecting the integral part IL-10 plays in both the induction and expression of the Th2 response to helminths [ 23].
Application of LY367385 (100 µ m, n = 6) prior to LFS (2 Hz, 1200 pulses) resulted in a significant impairment of both LTD induction and expression (Fig. 3) compared to controls (n = 12; anova: within factor F1,23 = 28.7899, P = 0.0001; between factor F1,23 = 2.729, P = 0.0002).
Glutamate (Glu), the major excitatory neurotransmitter, is involved in the induction and expression of both LTP and LTD, and, therefore, extensive research has focused on the role of Glutamatergic transmission in the pathophysiology of migraine.
The present study was designed to examine whether both induction and adaptation of brain Fos expression during acute stress depend on the intensity and duration of stressors.
HSP70 induction and expression kinetics at different temperatures and time durations were also studied.
These cultures were infected with EBOV and analyzed for cytokine/chemokine induction and expression of apoptosis-related genes.
Several studies indicate that both fear conditioning-induced neuronal plasticity and LTP at amygdaloid synapses share common mechanisms of induction and expression [9], [10].
Thus, Ng CaM interaction can provide a mechanistic link between induction and expression of postsynaptic potentiation.
Because the catabolic effect of cytokines on cartilage consists of both induction of MMP expression and downregulated expression of cartilage matrix genes, we tested the effect of small molecule inhibitors on mRNA expression of these genes.
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