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The constraints mentioned both in the structured and in-depth interviews were lack of resources particularly guidelines, and refresher training which are essential for knowledge update.
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It then examines the WIPO Development Agenda in light of this history and identifies possible paradigm shifts discernible both in the structure of the Agenda and in preliminary considerations regarding its implementation.
In general the detonation suffers a disruption both in the structure and velocity but recovers after some distance downstream of the obstacle.
In combination, these techniques confirm that the protein is an octamer both in the crystal structure, and in solution.
The observations by SEM indicated remarkable differences both in the structure and dimension of the pores between intact and atelocollagen sponges.
Since then, considerable improvements of the method have been achieved both in the structures of the spin traps, the EPR methodology, and the design of the experiments including appropriate controls.
Directional coarsening was clearly visible in the precipitate morphology and was measured quantitatively both in the structure function and in the amount of interface pointing in the x or y direction.
Initially, subspecialisation occurred based on different modalities in the 1970s and 1980s, while later organ-system based subspecialisation became much more appropriate and was gradually adopted both in the structure of radiological services and in the training curricula.
This diversity is seen both in the structure and action of systems involved in synthesis of diffusible antibiotics and proteinaceous toxins [ 5, 6].
We believe the likely positions of protons (both in the structure with the triazole ThDP bound and in the ThDP ylid-bound state that it mimics) are as shown in Figure 6A.
The respective physiological thioester substrates targeted by YdiI and YbdB, namely, 1,4-dihydroxynapthoyl-CoA and (hydroxy benzoyl- holoEntB, differ both in the structure of the appendage to the phosphopantetheine thiol moiety (viz., adenosine-3′, 5′-diphosphate 5′-diphosphateain of EntB) and in the structure of the organic acid moiety (1,4-dihydroxynapthoic acid vs (hydroxy)benzoic acid).
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