In particular, both the severity and speed of onset of age-related changes, such as wrinkle formation and loss of elasticity, are enhanced in photoaged (also termed extrinsically aged) as compared with aged, photoprotected, skin.
"While the N.H.L.P.A. does not condone Sean's comments, which were clearly inappropriate, the discipline imposed by the Commissioner is unprecedented both in its severity, as well as the process by which it was handed down," the statement said.
There was apparently declining trends both in frequency and severity in the decade after the pass of the Act.
In the present study, both the severity of symptoms and the physical function scales will represent the primary outcome, whereby a minimum of 0.5-point change in each will be required for the treatment to be considered a success.
In addition, the fact that expression of the disease phenotype is variable both in the age of onset and severity suggests that additional factors may be required to induce disease, such as stress and activity level [ 30].
Individuals affected with SLI represent a fairly heterogeneous group both in terms of the severity of their primary expressive and receptive language symptoms as well as in the extent to which additional areas (academics, peer relations) are affected (cf. Schwartz, 2009).
Ding et al. found both increases and decreases in the severity of knee cartilage defects and osteophytes within 2 years in a cohort with a mean age of 45 years and a 17% incidence of knee OA (Ding et al. 2006).
Retaliation against union leaders in both the severity and frequency; we are seeing is a huge obstacle to industrial peace..
Although the product causes significant reductions in both the severity and the duration of HAE attacks, the approval for this indication is still pending.
