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Hypoxic-ischemic encephalopathy (HIE) is the most important cause of cerebral damage and long-term neurological sequelae in the perinatal period both in term and preterm infants.
The reported mean age of emergence of the circadian rhythm was between the second and third month of postnatal life both in term and in preterm infants.
Because the need for resuscitation cannot be predicted prior to delivery, all birth attendants should be proficient in this practice and have the appropriate equipment available both in term and preterm births [ 54].
Perinatal asphyxia-induced brain injury is one of the most common causes of morbidity and mortality, both in term and preterm neonates, accounting for 23% of neonatal deaths globally.
Neonatal sepsis is a major cause of mortality and morbidity and has been implicated in the causation of perinatal brain damage and cerebral palsy, both in term and preterm infants [ 1, 2].
Hypoxia ischemia (HI) is the most common cause for perinatal brain injury both in term and preterm infants. 1, 2 In preterm infants, perinatal brain injury is mainly localized in the white matter; however, there is increasing evidence that cortical and subcortical gray matter are also involved.
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