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Since GST protein catalyzes the conjugation of electrophile to GSH, therefore alteration in this protein both in expression and activity might affect the individual response to the oxidative damage or inflammation resulted by lead exposure.
Paxillin, a key signaling protein downstream of integrin, was similarly found to be dramatically enhanced, both in expression and phosphorylation on Y195, Y141 and S178, in PRL-3-ablated cells.
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In tumour samples, Dsc2 showed both a reduction in expression and a relocalisation from the membrane to the cell cytoplasm.
Four proteins CA9, MLH1, mTOR, and BCL2 showed both significant changes in expression and increases intratumoural variance with sunitinib.
These data indicate good agreement between methods with respect to both regional differences in expression and the maturational trajectories.
It requires more subtle use of the voice, both in dynamics and in expression, and then colours".
Messina detects both consistent and inconsistent differences in expression and grants the experimenter great flexibility, but favours large margins.
These data demonstrated that fasudil prevented the HG induced increase both in Rho/ROCK expression and activity in endothelial cells.
Nevertheless, BTG2 was significantly down-regulated in tumours from dead patients compared to tumours from alive patients, both in overall expression and cell membrane specific expression.
We propose that the duplication and structural divergence of Gal-1B away from Gal-1A led to specialization in both expression and function in the sauropsid lineage.
In prostate cancer, a switch in both integrin expression and in the secretion of an aberrant ECM are associated with progression to invasion [ 8].
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