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There has been a growing interest in the development of this type of micro cells in the last years, resulting both in experimental studies (operating conditions, cell design and new materials) and in modeling studies.
Cell-based therapy, aiming at replacing the lost medium spiny neurons (MSN) with primary fetal striatal cells, has had some success at modifying the symptoms both in experimental studies and clinical trials.
Recently, much attention has been focused on the use taxol on glioma, both in experimental studies and in clinical trails [ 8].
The process of lipid peroxidation accompanied by excess production of MDA has been well documented both in experimental studies with cells infected by specific pathogens [ 3] and in systemic infections complicated by sepsis and leading to death [ 4, 5].
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In experimental studies, both pre- and post-ischemic administrations of vanadium compounds have been shown to be cytoprotective.
By mixing restorable polymers and ß-TCP, the biomechanical properties, resorption behaviours and osteoconductivity of both materials have been enhanced in experimental studies [2, 20].
In experimental studies, both DDT and DDE have been associated with adipose dysfunction (Howell and Mangum 2011; Moreno-Aliaga and Matsumura 2002).
Tear film stability has been used as an objective measure for air borne pollutants, both indoors [ 10], outdoors [ 11] and in experimental studies [ 12, 13].
The retrieved biomarkers and the major findings from key studies using these biomarkers are listed in Tables 1, 2, 3, 4, 5, 6, 7, 8 and 9. Of the 178 biomarkers, 18 had been evaluated in experimental studies only, 58 in both experimental and clinical studies, and 101 in clinical studies only.
AMG participated in experimental studies.
These have been applied to animals with spinal cord injuries in both experimental studies and clinical trials in order to evaluate functional recovery [ 1– 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com