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Molecular biologists who study any one of these pathways may select candidate gene targets of these pathways uncovered by this study and validate the expression patterns both in experimental models (models using prostate cells in particular) and in human prostate tumor specimens.
These nanoparticles can successfully transfect both dividing and non-dividing cells, and have been shown to be effective agents, both in experimental models as well as in a phase I/IIa clinical trial for cystic fibrosis, in delivering genes of interest to multiple tissues, including the lung, retina, and brain [7], [8], [10], [11], [13] [15].
PSMA has been targeted to deliver therapeutic nanoparticles both in experimental models and in cancer patients.
ESWL for renal stones has been occasionally associated with vascular damage, both in experimental models and in patients [ 4– 9].
More insight is needed regarding the pathophysiological conditions associated with presepsin release, both in experimental models of sepsis and in well-characterized patients.
Thus, it seems that excess of deaths, myocardial ischaemia and proarrhythmia are interrelated both in experimental models and in post-MI patients.
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And although the β-blockade is still very contradictory in patients with sepsis, both studies in experimental models and in septic patients with previous prescription of β-blockers have shown a potential role of these drugs in patients with sepsis [2, 3].
Thus, the results of our study further highlight the relevance of studying both sexes in experimental models of maternal diet and may provide critical insight regarding the influence of FA in programming sex-biased methylation pattern.
Many basic researches have proved that statins can be helpful for the treatment of PH both in vitro and in experimental models.
Recent studies have shown that regulatory T cells play a crucial role in the escape mechanism of Plasmodium spp. both in humans and in experimental models.
Numerous studies have implicated NHEJ as a key suppressor of lymphoid tumorigenesis, both in humans and in experimental models [ 3- 5].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com