ICAM1, an adhesion molecule that binds to LFA-1, is a gene that is strongly regulated by NF-κB signaling and is upregulated on a variety of cell types in response to TNFα signaling including synovial fibroblasts and especially vascular endothelial cells, both of which are highly represented in the inflammatory rheumatoid synovium [ 41, 42].
Gene function categories associated with metabolic process are highly represented in both transcriptomes.
Some protein families are highly represented in both latewood and mature wood, suggesting possibly similar transcriptional regulation in these developmental stages.
There was generally good concordance of the virtual data with the RT-PCR data; notably, Psg21 and Psg23 are highly represented in both datasets.
Within this data there might also be a bias for some specific cell types such as stem cells, which are highly represented in both data sets.
The three known miRNA families that were most highly represented in both Musa A- and B-genomes showed similar patterns of distribution across the chromosomes of both genomes, suggesting synteny of A- and B-genomes.
Stress reactions were prevalent 9 months after the event, with sadness (69%) and avoidance (59%) being highly represented in both directly and indirectly affected groups, whereas, nightmares (60%) and feelings of guilt (50%) were only frequent in those directly affected.
Interestingly, although mussels and oysters shared less than 10%% of proteins with a sequence identity over 80%% (Fig. 3), the response to infectious disease and cancer were highly represented in both transcriptomes [ 29].
Enriched GO categories corresponded well with enriched KEGG pathways, with immune-related functions highly represented in both [e.g., the GO category "immune response" (GO 0006955) having an FDR= 2.08 x 10-14; not shown].
Their overall distribution among the various known TF protein families was compatible with previous studies in other legumes such as soybean, chickpea, pigeonpea and cultivated peanut [ 4, 28, 30, 50, 51], with bZIP, MYB, NAC, bHLH, AP2-EREBP and WRKY highly represented in both A. duranensis and A. stenosperma transcripts.
