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The rates of both growth and cell division can vary widely in different body parts.
The effect of 5-fluorouracil (5-FU) on the growth and cellular proliferation of hepatoma 3924A was studied using the following parameters as indices of tumour response: (1) volume measurements, (2) cell kinetic analysis including estimates of both growth and cell loss fractions, (3) changes in tumour histology and (4) tumour DNA content and DNA synthesis.
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myr-Akt expression was sufficient to drive both growth and cell-cycle re-entry (as evidenced by extensive pH3 labeling) in quiescent neuroblasts in the absence of the nutritional stimulus.
This indicates that optimum Sr addition could enhance both the growth and cell viability of the PEO-produced Sr-HAp coatings.
MET1 independently controls both endosperm growth and cell division and elongation of the integuments.
In vivo, ganetespib's coordinate impact on both cell growth and cell division results in potent antitumor activity in JAK/STAT-driven models of human leukemia.
The concomitant impact of ganetespib on both cell growth and cell division signaling translates to potent antitumor efficacy in mouse models of xenografts and disseminated JAK/STAT-driven leukemia.
Population growth requires both cell growth and cell proliferation.
Nuclear PTHrP is able to regulate both cell growth and cell death.
Evidence indicates a crucial role for TRP channels in regulating both cell growth and cell death.
Such actions of polyamines may help explain how they can promote both cell growth and cell death and can show such a complex involvement in aging, stress and diseases.
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