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There were 89 subjects in the protocol group and 85 in the control group with both groups well matched for age, sex, weight, Parsonnet cardiac risk score, APACHE II score, and type of surgery.
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Groups were well matched for subject numbers, gender and age, with the dementia groups well matched for age at onset and duration of dementia, Mini-Mental State Examination and total Cambridge Cognitive Examination scores.
The responses of the principal investigators to those issues indicate that both groups were well matched, with median Glasgow Coma Scale scores of 3 in both groups and interquartile ranges from 3 to 4 or 5 [ 6].
Both groups were well matched for demographics: intervention and control group respectively, mean age of 68.9 (±14.7) vs. 70.9 (±13.2), p = 0.08; admission after cardiac surgery 21 (7.1%) vs. 26 (8.3%), p = 0.40; admission after percutaneous interventions 60 (20.3%) vs. 59 (18.8%), p = 0.55.
We recognise that there were significant differences between the pre- and post-protocol groups with respect to the indications for warfarin, however, patients in both groups were well matched for age, gender and ASA grade.
Both groups were well matched.
Both groups were well matched for age and sex.
Both groups were well matched for age, heart rate, and total and LDL cholesterol.
Both groups were well matched before ICU admission, with an overall mortality of 50%.
Both groups were well matched in terms of age, height and body weight.
Both groups were well matched with respect to age and gender.
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