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In both groups, the norepinephrine infusion was continued until the resolution of septic shock.
In both groups, the norepinephrine and dopamine concentrations did not vary significantly throughout the study, which is in accordance with the other measurements.
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Table 2 compares the baseline characteristics in the two changeover groups; the norepinephrine dose and HR were significantly higher in the SIP group than in the QC group.
Table 2 compares the baseline characteristics in the two changeover groups; the norepinephrine dose and HR were significantly higher in the SIP group than in the QC group.
In VASST, there was a trend to more digital ischemia in the vasopressin group versus the norepinephrine group (2.0% versus 0.5%, P = 0.11).
In the gentisic septic group and the norepinephrine (NE) septic group, both treatments increased MAP back to the baseline value.
Other important groups include the norepinephrine reuptake inhibitors (NRIs), the serotonin-norepinephrine reuptake inhibitors (SNRIs), and the atypical antidepressants, a disparate group of agents that possess unique structural features and mechanisms of action.
ICAM-1 and cGMP correlated positively in both groups with the intravenously administered norepinephrine dosage in early and late sepsis.
Cardiac index and cardiac power index increased significantly more in the epinephrine group than in the norepinephrine group.
These effects were less obvious in the fluid loading group and in the norepinephrine group as numerical changes were virtually absent.
The heart rate was significantly lower in the vasopressin group than in the norepinephrine group (first 4 days).
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