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For both groups the grade of toe deformity increased from the first to the fifth toe.
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While the final course grades revealed a wide range of scores spanning from a low of "F" to a high of "A" for both groups, the final course grades obtained by both groups corresponded to a "C".
Both groups of the grade 2 cartilage samples and the grade 3 cartilage samples had a significant increase in Rbone in comparison with normal cartilage (p < 0.05).
In both groups, the mean overall grade was 6.6 (on a ten-point scale).
However, there was no difference between the both groups (grade 0 1 and 2 3) of RC patients in all parameters studied (Fig. 2a- d).
For both groups, the most commonly noted Grade 3 toxicity was mucositis (23 C, 5 S), pharyngitis (20 C, 2 S) and moist skin desquamation (18 C, 3 S).
When comparing MRI grades of all samples among the groups, the grade 3 group showed a significantly higher level of SIRT1 mRNA expression than the grade 2 and grade 4 groups (P < 0.05).
Histopathological examination of the cornea showed the number of polymorphonuclear leucocytes was below 50 for both groups (mild grade).
In both groups, grade 3 adverse events were infrequently reported and no serious adverse events were considered causally related to vaccination.
The percentage of doses followed by at least one unsolicited adverse event within the 31-day post-vaccination period was comparable in both groups and the incidences of grade 3 unsolicited symptoms were low.
In both groups, Brooke's grading system of mobility was scored [ 18].
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