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At 3 months follow up, the reduction seen for both groups remained significant.
The improvement from baseline scores demonstrated at week 4 in both groups remained significant for most outcomes at week 8.
Differences in IGF-I bioactivity, total IGF-I, IGFBP-3, total IGF-I/IGFBP-3 molar ratio between both groups remained significant after correction for age, gender and BMI (p=0.001, p<0.01, p<0.01 and p<0.001, respectively).
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The increases in both intervention and control groups remained significant in the multivariate analysis.
After 2 weeks, an increase in both groups was found but the difference between the two groups remained significant during the total study period (P<0.05).
Following ANCOVA analysis, the difference between groups remained significant for all genes in all brain regions, except for Sp1in the striatum.
Again, differences in levels of proliferation between the two tissue groups remained significant with elevated cell cycle entry in cultures derived from peripheral regions (Figure 2F).
Simple contrast analyses showed that the differences between the Control and Experimental groups remained significant for between 31 and 38 days.
Differences between all groups remained significant.
With use of either restriction, differences between case and control groups remained significant.
The difference between the ≤MDA and HDA groups remained significant at 24 weeks.
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