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Since both groups of proteins are involved in gene silencing one might expect there to be a significant overlap between the two groups.
Both groups of proteins were subdivided into oscillating and non-oscillating proteins.
Indeed, removing transcript abundance from the PLSR analysis revealed that the prediction of protein abundance for both groups of proteins was affected.
Both groups of proteins are known to interact with viral proteins [ 28, 29], which may be a potential source of selective pressure.
We found that both groups of proteins tend to form bigger network components than a randomly selected of proteins consisting of 10% of the network nodes (P = 0.004 and 0.0002, respectively, randomization tests).
A recent spatio-temporal gene expression analysis showed that the genes of both groups of proteins are expressed in the brain and nervous system during early stages of zebrafish larval development.
Similar(51)
In both groups of patients, abnormal proteins build up in the brain and potentially kill off neurons.
Members of both groups of HMG-box proteins also bind altered nucleic acid structures such as 4-way junctions [ 11- 13] and cisplatinated DNA [ 14].
Nonetheless, several groups have isolated Abs with broad inhibitory spectrum which bind to highly conserved epitopes in diverse influenza viruses from Group 1, Group 2, or both groups of the HA protein using naïve or immune phage display Ab libraries, Ab cloning from sorted plasmablasts and plasma cells, or hybridomas of memory B cells.
However, these alterations were reversible in both groups of animals fed normal protein diets and protein-restricted diets.
This suggests the Su TPE s represent a novel group of regulatory proteins involved in gene silencing, distinct from both the Polycomb and Su var) groups of proteins.
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