These results were supported by quantification of fungal burden in organs of both groups of mice.
Once in the barns, both groups of mice were placed on the same normal diet.
Nevertheless, OVA-specific T cell proliferation was similar in both groups of mice.
Both groups of mice performed admirably in the water maze, bettering their performances from the earlier trial.
χ2 test was used to compare the rates of infection between both groups of mice at each week post-infection.
Moreover, the success rate of transfection by IUE was similar in both groups of mice (Supplementary Fig. 1a,d).
In a second series of experiments, both groups of mice were injected with a lower dose of LPS.
A significant reduction of renal bacterial colonisation was observed in both groups of mice (P < 0.05) after P. mirabilis challenge.
While both groups of mice developed blood-stage infection, the control mice showed a rapid increase in parasitemia and became moribund on day 19 after infection.
In future studies, we intend to explicitly explore this pathway by among other things, measuring serial serum cortisol levels on both groups of mice.
And while glucose metabolism often behaves quite differently in lean mice than in obese mice, this mechanism was seen in both groups of mice.
