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Thigh muscle CSA increased in both groups at week 14, but the magnitude of the increase did not differ significantly between groups.
All assessments are repeated for both groups at week 18.
Subsequently, group differences reached almost 180% before declining to zero in both groups at week 11 12.
In detail, AMCV IgM titers decreased significantly by 73.95 % in RRs (P <0.0001) and by 62.5 % in NRRs (P = 0.03), with a substantial difference between both groups at week 24 (P = 0.0003) (Fig. 4).
Safety outcomes were similar between both groups at week 104, except patients in the add-on group exhibited numerically higher rates of elevated transaminase levels than patients in the switch group, consistent with week 24 and week 52 results.
Results of all outcome measures are summarised in Table 2. Performance in the 25 m walk test, stair climb test and chair rise test improved (p≤0.001) in the RT and NMES groups at week 8 compared to week 1, and the improvements were maintained in both groups at week 14.
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Our study reports that incidences of proteinuria were not significant for both groups at weeks 0 or 48.
The Nail Psoriasis Severity Index values persevered in both groups at weeks 38 and 50 (placebo crossover to infliximab occurred at week 24), also regardless of PsA history.
Relative to baseline, CTx, osteocalcin, BSAP, and P1NP increased; vitamin D decreased in both groups at weeks 48, 96, and 144.
Interviews were repeated for both groups at 4 6 weeks, 10 12 weeks, 16 18 weeks (the standard practice group only, to occur 4 6 weeks after receipt of the palliative care service) and 24 26 weeks.
After the baseline interview, interviews were repeated for both groups at 6 weeks, 12 weeks, and 24 26 weeks (final interview).
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