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Mothers in both groups are assessed by means of a wide-range of psychometric instruments.
Patients of both groups are assessed at the baseline and at the end of six months.
After three months, both groups are assessed according to Process B. At the end of the intervention period (after six months), both groups are assessed according to the complete protocol (Processes A, B, and C).
Differences in total costs between both groups are assessed and confidence intervals are estimated using bias-corrected and accelerated bootstrapping with 2000 replications [ 54].
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Both groups were assessed 9 months after their initial assessment (month 0).
Both groups were assessed at baseline, 3 and 6 months.
Both groups were assessed before the program (T1) and were monitored after 2 months (T3 follow-up).
Differences between both groups were assessed using the Mann–Whitney U test.
Furthermore, differences in the amount of hydrogen peroxide (H2O2) produced by S. sanguinis isolated from both groups were assessed.
Both groups were assessed separately for marital satisfaction and QOL along with demographic details followed by appropriate statistical analysis.
Clinical symptoms in both groups were assessed by direct interview with the Diagnostic Interview for Genetic Studies (DIGS), a widely used instrument with established reliability (Nurnberger et al. 1994).
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