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At T12, both groups achieved a significant reduction of PASI values that, however, was higher in patients treated with both topical steroids and oral curcumin than in patients treated only with topical steroids.
At the end of the 52 weeks, both groups achieved a mean HbA1c level of 6.6%, FPG was reduced by >40 mg/dL, and body weight was reduced by >4 kg.
Between 35% and 37% of both groups achieved a mACR20, 20 22% a mACR50 and 10 12% a mACR70; none of these differences were significant in unadjusted or adjusted analyses.
Both groups achieved a conduct problems score in the normal range (scores >3 are indicative of dysfunction), but girls in the high-DHA group scored significantly higher compared with girls in the standard-DHA group (see web appendix B).
At the end of study drug administration, both groups achieved a significant decrease in the level of glycated hemoglobin (7.1% in the glipizide group and 7.0% in the metformin group).
Similar(55)
After a 6-month follow-up, both groups achieved an insignificant reduction in NYHA class.
26, 27 In the present study, over 85% of patients in both groups achieved an average HbA1c <8% at 6 months, and therefore adjusted to current goals.
The authors demonstrated the equivalence of both the simple strategy and the more elaborate carbohydrate-counting strategy in achieving glycemic control; almost one-half the participants in both groups achieved an A1C <6.5%.
Exenatide and insulin glargine treatment resulted in similar reductions in A1C (0.8 ± 0.1 and 0.7 ± 0.2%, respectively; P = 0.55), with both groups achieving a mean A1C of 6.8% at 52 weeks.
At week 12 (LOCF), 65.2% of patients in both dapagliflozin groups achieved a ≥0.5% decrease from baseline A1C versus 15.8% in the placebo group.
At the end of treatment, both treatment groups achieved a mean level of HbA1c below 7.0%, with no significant difference between treatments (P=0.177; fig 2 and table 2).
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