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Summary statistics were reported for both gene expression values and clinical covariates.
Univariate Cox regression models [ 16] were fitted to evaluate the association of both gene expression values and clinical covariates with overall and disease-free survival.
To assess whether the gene expression values offered any gain in prediction over clinical parameters, models with clinical covariates significantly associated with disease mortality and recurrence were compared with models including both gene expression values and clinical covariates.
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Although both genetic and gene expression values of M66 were also unexpected, they support the previous study of Condón et al. [ 3], which placed M66 out of the contemporary group of elite lines.
Both axes are relative gene expression values in base-2 logarithm against the averaged expression levels of each gene.
In standard gene centering, gene expression values are typically expressed relative to the median (or mean).
This is in contrast to the TRANSBIG validation study, where considerable heterogeneity in both estimated model coefficients for gene expression values and predictive accuracy existed between ER+ and ER- subsets of breast cancer.
Genes were divided into three clusters (i) 36 genes which have lower gene expression values in both AD-iPS neuron compared to H9 neurons, among them PSMC1, PSMA5, NEDD8.
software [ 106] in two ways: first by comparing the relative gene expression values between both cultivars in the same tissue under the same stress conditions and second by comparing the control (without stress) with the stressed samples of the same cultivar.
Relative gene expression values were normalized against GAPDH.
p53-Dependent gene expression was calculated from the ratio of the gene expression values in wild-type p53 cells and in mutated p53 cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com