Gene prioritization from microarray data was improved considering both, gene expression and genes co-expression (connectivity) information.
Together this data suggests that a change in replication timing is also associated with a concerted change in both gene expression and the epigenetic status of the promoter.
Some reports demonstrated that changes in cell shape precede and trigger dramatic modifications in both gene expression and enzymatic function.
The biochemical functions of the acyltransferases within both clusters have not been addressed; however, it seems that neofunctionalization occurred with respect to both gene expression and protein function, conferring a role for CS in capsaicinoid synthesis after recent gene duplication.
The goal of unravelling the underlying mechanisms is attainable by analysing both gene expression and epigenomic changes using frequent sampling of queen, worker and inter-caste larvae from the moment of hatching up to pupation.
Synonymous mutations are often thought to impact both gene expression and fitness through modifications to codon usage bias, mRNA stability or protein folding, but these mechanisms seem unlikely explanations for our results.
Furthermore, large-scale transcriptomic and proteomic analysis highlighted the significant modulation of both gene expression and protein abundance at the infection site, inhibiting the establishment of systemic acquired resistance.
In CE culture with ECM functionalization, chondrocyte dedifferentiation was significantly inhibited vs. SS cultures, as evidenced by both gene expression and pellet cultures.
These observations indicate that repetitive DNA elements mediate chromatin accessibility in proximal promoter regions and the repeat content of promoters is relevant to both gene expression and function.
Consequently, HP1 has many important roles in chromatin architecture and impacts both gene expression and gene silencing, utilizing a variety of mechanisms.
Thus, no side effects on both gene expression and cell metabolism were reported in all examinations.
