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Approximately 21.5 % caecilian genes showed the slowest evolutionary rate, i.e., slower than both frog and human.
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Senior author Peter Narins, a biologist at the University of California, Los Angeles, believes that the results will increase our understanding of the hearing mechanisms in both frogs and humans.
They are not: both frogs and humans (and birds and lizards and cats) are equally closely related to fishes because as tetrapods they share a common ancestor to the exclusion of bony fishes.
There are much fewer LIRs in yeast, fruitfly, pufferfish and chicken than in Caenorhabditis elegans, zebrafish, frog and human.
The deduced CpC8α exhibits 89%, 49% and 44% identity with nurse shark, frog and human orthologs, respectively.
Ostrich ADH2 shares 81.6%, 77.3% and 68.8% identity with turtle, frog and human ADH2, respectively.
Additional file 6: Genome-wide RRTs of Banna caecilian, Western clawed frog and human using protein sequences.
This activity was mostly accounted for by differential activation to frog and human sounds when contrasted with horn sounds.
RRTs were performed on the protein sequences of 623 orthologous genes, with Banna caecilian, Western clawed frog and human as the ingroups and Indonesian coelacanth as the outgroup.
Therefore these duplication events in the frog and human genomes may have happened separately after the divergence of amphibians from mammals.
According to their patchy distribution, several TE superfamilies are candidates for HGT: MuDr in human; Merlin in stickleback, zebrafish, western clawed frog, and human (Feschotte 2004); Chapaev in the green anole, fugu, and platyfish; and P in platyfish and coelacanth.
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