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Statistical comparison of all rabbit antibodies from the three-antigen (Gp 2, n = 8) and seven-antigen (Gp 1, n = 9) immunisation groups, both formulated in Co-Vaccine HT, showed no significant difference in mean % antibody depletion by all six competitor antigens/mixtures (Table 1, Gps 1 & 2).
Specificity profiles of antibodies from rabbit immunisations with the three-antigen (DiCo mix, Gp 2) and seven-antigen (DiCo mix + AMA1 alleles from FVO, HB3, 3D7 and CAMP strains of P. falciparum, Gp 1) vaccines, both formulated in CoVaccine HT™, were determined by a standardized competition ELISA with the three DiCo proteins used separately as capture antigens.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com