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Aeromonas hydrophila is a ubiquitous Gram-negative bacterium that often leads to motile aeromonad septicemia in both fish and human [1], [2], characterized by gastroenteritis, wound infections and systemic illness [3].
The TAPBP, DAXX, ZBTB22 and KIFC1 genes are conserved in the same order in both fish and human (Fig. 2).
The Tyr182 in the internal loop D of DrAqp3b is conserved in both fish and human AQP3 but not in other zebrafish GLPs and DrAqp1a.
These results suggest that the susceptibility of triploids to opportunistic pathogens (important in both fish and human health) or potential probiotic treatments may be increased in comparison to diploids.
In addition, we found both fish and human pathogens share many features and it may be possible to use the fish parasites as models to enhance our knowledge about host parasite interactions for this important group of pathogens.
We categorized the duplicated enhancers into those, with duplicated copies only in fish lineage (only a single counterpart in human), duplicated copies only in human (only a single counterpart in fish), and the ones that contains duplicated copies in both fish and human lineages.
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In 2007, shortly after the stickleback genome was sequenced, Miller used crossbreeding to track down genes involved in pigmentation in both fish and humans.
The particular fish oils that benefit the health of both fish and humans, called EPA and DHA, are not in fact produced by fish themselves but instead accumulated by eating marine microbes.
Aeromonas spp. were selected as some species, e.g. A. hydrophila, include pathotypes of clinical significance for both fish and humans [20] and are also ubiquitous, representative members of the aquatic microbial community.
Approximately 20 years after industrial aquaculture had begun, evidence emerged that ARGs were transferred between aquatic bacteria that are pathogenic to both fish and humans (Cabello 2006; Ryu et al. 2012).
By studying pathogens that are virulent for both fish and humans and that mediate disease states in the zebrafish identical to those found in human streptococcal infections, common virulence strategies shared by a number of gram-positive pathogens can be identified.
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