Sentence examples for both expression and function from inspiring English sources

Additionally, we also illustrate the disparity between gene expression and protein function in simple 2D culture modes, and that recreation of a physiologically mimetic 3D environment is necessary to induce both expression and function of cultured hepatocytes.

Interestingly, we have previously shown that expression and function of nuclear receptors such as the PPARs, can be regulated by gut microflora regarding both expression and function [20], [21].

Like Dlx5, Runx2 (encoding two isoforms that differ at their amino-termini) is a multifunctional regulator of both chondrocyte and osteoblast differentiation [41] and the two factors have some remarkable parallels in both expression and function.

For example, Nudelman et al. [40] recently described a novel NB54 aminoglycoside with reduced toxicity and enhanced suppression of disease-causing premature stop mutations in cells that originated from various hereditary diseases which improves both expression and function of the corrected protein.

10 Both expression and function of SGLT2 are increased in patients with T2DM.

Both expression and function of the Na-Ca-exchanger (NCX) appear to be normal in these experiments [ 16].

Therefore, both the expression and function of IFNλs is much the same as for the type I IFNs.

These observations indicate that repetitive DNA elements mediate chromatin accessibility in proximal promoter regions and the repeat content of promoters is relevant to both gene expression and function.

Nevertheless, equivocal data are available on both the expression and function of these enzymes in coronary arteries (CA).

As the GR-α and GR-β isoforms originate from alternative splicing of the same gene, the only accurate way of specifically quantifying the GR-β isoform is using qPCR, which precludes information about both protein expression and function.

Utilizing this method, we examined the effect of NSC23925 on both the expression and function of Pgp1.