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Probe sets induced or repressed by 1.74-fold or greater in both experiments were considered differentially expressed.

The entire experiment was performed twice, and only genes that showed a 2-fold or more difference from control in both experiments were considered deregulated (Tables S1, S2, S3, S4, S5, S6, S7, S8, S9, S10, S11 and S12).

Compounds identified as FabG ligands in both experiments were considered as hits.

The significant proteomic features common to both experiments were considered as suitable candidates for purification and identification.

Two independent experiments were conducted, and only phospholipids identified in both experiments were considered real hits and used in our analyses.

For stringent identification of genes having the most consistent impact on growth and survival of the analyzed cell lines, results of the replicate experiments were combined and siRNAs having a z-score greater than ± 2 s.d. for the measured Ki-67/cPARP signal ratio over both experiments were considered significant.

Similar(54)

Probe sets significantly increased at least twofold in IP RNA relative to input RNA in both experiments are considered OMA-1-associated, as described in the text.

The follow-up visits in both of the experiments were considered to be biannual during the duration of each trial.

Values that were < -2.0 or > 2.0 in both two independent experiments were considered significant and the mean values of the relative fluorescence ratio for each gene were calculated.

Values that were decreased or increased by > 2-fold or greater in both two independent experiments were considered significant and the mean values were calculated.

For inferring associations with cell lethality, set scores from both LB and M9 experiments were considered.

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