Sentence examples for both experimental models and from inspiring English sources

The ability to measure cardiac output led to the observation of an association between the development of a hyperdynamic circulation and survival in both experimental models and clinical septic shock [35 37].

The role of GALT in GVHD has been suspected on both experimental models and clinical observations.

Declining cardiac function is a significant source of mortality in both experimental models and in patients suffering from Chagas disease.

Data from both experimental models and clinical samples have identified important functions of PDGFRβ on pericytes and fibroblasts in the tumor stroma.

The pathogenesis of heart failure involves molecular mechanisms which are becoming better understood [1], [2] and studies in both experimental models and humans demonstrate the important relevance of dysregulated gene expression [1], [3].

Antibody-mediated immunity has been shown to be crucial in both experimental models and in human cases of pyelonephritis [ 30].

This is especially true in the field of carcinogenesis, where both experimental modelling and theoretical framework have been for a long time dominated by the SMT [ 14, 15].

Finally, exposure to heavy metals is associated with CD and sirenomelia in both experimental models (Ferm and Carpenter, 1968; Hilbelink and Kaplan, 1986) and in humans (Castilla et al., 2008; Orioli et al., 2009).

In both experimental models of IBD and in humans the mucus layer becomes more permeable to bacteria and is therefore considered critical etiological factors in this disease and possibly other intestinal disorders [ 28].

In the chronic phase of Chagas disease, TNF- α seems to be closely related to cardiac dysfunction owing to its negative inotropic effect, in both experimental models [ 38] and humans [ 39].

Recently, the discovery that angiotensin-converting enzyme 2 (aCE2), a member of the vasoprotective arm of the RAAS, is up-regulated in both experimental models of PH and human PAH has refocused attention on this system (Ferreira et al., 2009).