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Exact(7)
In cotransfected cells, Dyrk1A overdosage caused parallel changes in the splicing pattern of an AChE mini-gene, suggesting that Dyrk1A overdosage is both essential and sufficient to induce the observed change in the composition of AChE mRNA variants.
Unlike CeHMT-1, the NTE of ABCC1/MRP1 is both essential and sufficient for oligomerization.
Together, these outcomes provide strong evidence that the Nβ domain is both essential and sufficient for NaTrxh secretion.
In this system, FGF2 was both essential and sufficient for the formation of more differentiated structures, the lentoid bodies (Yang et al. 2010).
The reported LC sequence was shown to be both essential and sufficient for formation of RNA granules through trapping of RNA binding protein-containing LC sequences, including FMRP.
In the absence of both a functional piRNA pathway and L1 DNA methylation, G9a is both essential and sufficient to silence L1 elements.
Similar(53)
While much is known about 5'-UTR-dependent translational control in bacteria, the reported findings provide the first examples that both 5'- and 3'-UTRs are essential and sufficient to drive differential translational regulation in a prokaryote and therefore have to functionally interact in vivo.
Macrophage colony-stimulating factor (M-CSF) is essential and sufficient for osteoclastogenesis.
Ramakrishnan calls these "basic operators" in the sense that they are essential and sufficient to execute relational operations [51].
A first peptide signature is essential and sufficient to target AtBPC6-GFP thethe nucleus and nucleolus.
Our results suggest that the SH3 binding motif of Unc119 but not the SH2 binding motif is essential and sufficient for inhibition of Abl and Arg kinases.
More suggestions(16)
both essential and critical
both true and sufficient
both essential and expensive
both essential and non
both essential and specific
both essential and noxious
both essential and challenging
both insufficient and sufficient
both essential and optional
both achievable and sufficient
both essential and advantageous
both essential and inevitable
both essential and feasible
both essential and achievable
both essential and cost-effective
both essential and nonessential
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