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If, on the contrary, they are both essential and specific for the target domains, then the statistical biases within this region in natural ligands should be analogous to, or at least reminiscent of, the amino acid frequency patterns observed within the same positional window in artificial ligands.
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The conservation of DRP-1β and ZIPk and their gene organization across vertebrates, perhaps even from the very emergence of this subphylum, excludes complete redundancy and indicates some essential and specific roles for both kinases.
Peptidoglycan is an essential and specific component of the bacterial cell wall and therefore is an ideal recognition signature for the immune system.
One of the essential and specific functions of mTORC1 is the regulation of cell size.
Our work also suggests an essential and specific role of CaMid1 in caspofungin tolerance.
Aggrecan is an essential and specific proteoglycan of the ECM, which contributes to the effective neutralization of compressive forces.
These behavioural studies show the PSD95 SH3 domain has an essential and specific role in the sensitized response to tissue inflammation.
Therefore, we aimed to investigate the essential and specific roles of the cardiac CaMKII isoforms using new genetic models.
These hypothetical proteins have no known homology to proteins in the host and therefore could be essential and specific to parasite function during infection.
Together, these findings identify an essential and specific role for E2F6 in HOXC9 induction of growth arrest and repression of cell cycle genes.
Transcriptomic analysis revealed an up-regulation of flu and ex2, two of the key genes identified as essential and specific components of the O2 signaling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com