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Here, cubic splines with natural boundary conditions, i.e. the curvature at both end points is set to zero, are utilized.
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The effect on both end points was small.
Both end points are measures of larval development in frogs.
Both end points are used in most research protocols of adjuvant therapies in oncology.
As both end points are binary responder end points, identical logistic regression models using Proc GENMOD in SAS were used.
Polyploidization has been related to carcinogenesis and aging, and both end points are significantly affected by dietary restriction (DR).
Both end points were estimated by means of the Kaplan Meier method and the log-rank test was used for comparisons.
Both end points were also associated with the concentrations of brominated THMs but not chloroform in the exhaled breath of the swimmers.
Statistical dose response regression analyses for both end points were carried out by applying a best-fit approach (Scholze et al. 2001).
Minimal effects on both progression and survival were seen in 13% of studies; that is, the hazard ratio for both end points was close to one (0.9
To test for correlations, a complete set of data for both the candidate surrogate and true end points is required [ 14] and only half of all trials had quantitative estimates for both PFS/EFS and OS.
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CEO of Professional Science Editing for Scientists @ prosciediting.com