Sentence examples for both efficacy and selectivity from inspiring English sources

This approach suggests that evidence-based design of multi-target therapies may take advantage of hierarchical patterns of convergence to improve both efficacy and selectivity of disease-intervention.

The use of the synthetic SIRT1 activator SRT1720 has been proposed to selectively activate SIRT1 with greater potency, efficacy, and selectivity than resveratrol.

Drug-interaction screens may identify combinations with increased efficacy and selectivity for specific cell lines or phenotypes8.

This analysis presents a model framework for evaluating drug combinations with increased efficacy and selectivity against pathogens or tumors.

Using FCB and phospho-specific flow cytometry, we screened a small-molecule library for inhibitors of T cell receptor and cytokine signaling, simultaneously determining compound efficacy and selectivity.

Having demonstrated the efficacy and selectivity of EpCAM-directed survivin RNAi in vitro, we proceeded to evaluate the chimera-mediated survivin RNAi in vivo.

To assess the efficacy and selectivity of inhibiting MYC with interfering peptides in breast cancer cells, we engineered OmoMYC with an N-terminal FPP (namely FPPa, Fig. 1a).

In conclusion, surface modification of liposomal DOX with engineered p18-4 peptide at an optimum density can improve the antitumor efficacy and selectivity of liposomal DOX.

In conclusion, the incorporation of IM in niosomes enhanced its efficacy and selectivity toward cancer cells, presenting a promising tool to fight cancer using this approach.

The direct visualization of protein kinase activity in living cells provides a genuine assessment of the efficacy and selectivity of these inhibitors in a physiological setting.

The most potent compounds (1.2 1.3-fold the CQ on the W-2 strain) can be considered as promising 'lead compounds' to be further optimized to improve efficacy and selectivity against Plasmodia.